골다공증 치료 약제와 턱뼈괴사증의 이해
Understanding osteoporosis treatment drugs and jaw bone necrosis
김진우, 김선종,
소속 상세정보
김진우 ( Kim Jin-Woo ) - Ewha Womans University School of Medicine Departments of Oral and Maxillofacial Surgery
김선종 ( Kim Sun-Jong ) - Ewha Womans University School of Medicine Departments of Oral and Maxillofacial Surgery
Abstract
Since the first report of osteonecrosis of the jaw (ONJ) associated with bisphosphonate (BP) administration in 2003, there have been many efforts to establish the pathophysiologic nature of this disease. Given that its pathogenesis is still poorly understood, and the global dependence on BP use and the entry tor aging society, there is a pressing need of related investigations. In this article, the authors aimed to assess the possible ONJ-inducing drug including BPs, Denosumab, Romosozumab, and etc., and investigate the actual diagnosis and treatment of ONJ.
키워드
osteonecrosis of the jaw; osteoporosis; bisphosphonates; denosumab; romosozumab
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